Monitoring functional immune responses with a cytokine release assay: ISS flight hardware design and experimental protocol for whole blood cultures executed under microgravity conditions.
Judith-Irina Buchheim, Matthias Feuerecker, Michele Balsamo, Marco Vukich, Merel Van Walleghem, Kevin Tabury, Roel Quintens, Randy Vermeesen, Bjorn Baselet, Sarah Baatout, Bernd Rattenbacher, Inês Antunes, Thu Jennifer Ngo-Anh, Brian Crucian, Alexander Choukér · PubMed · 2023
The resultant data promises to offer a more accurate understanding of the stress-induced neuroendocrine modulation of immunity during space travel providing valuable insights for the scientific community. Furthermore, the versatile nature of the RT suggests its potential utility as a testing platform for various other assays or sample types.