Inside Back Cover: Topochemical Ene–Azide Cycloaddition Reaction (Angew. Chem. Int. Ed. 47/2021)
Ravichandran Khazeber, Kana M. Sureshan · Angewandte Chemie International Edition · 2021
Topochemical reactions are lattice-controlled reactions that occur in crystals or other confined media. However, only a handful of topochemical reactions are known so far. In their Communication on page 24875, Ravichandran Khazeber and Kana M. Sureshan report a new topochemical reaction: a topochemical ene–azide cycloaddition reaction, in which a proximally placed azide and an alkene undergo a cycloaddition reaction to form triazoline in a regiospecific, stereospecific, and single-crystal-to-single-crystal fashion.