Structural, QSAR, machine learning and molecular docking studies of 5-thiophen-2-yl pyrazole derivatives as potent and selective cannabinoid-1 receptor antagonists
Riadh Hanachi, Ridha Ben Said, Hamza Allal, Seyfeddine Rahali, Mohammed Abdulaziz Alkhalifah, Faisal I. Alresheedi, Bahoueddine Tangour, M. Hochlaf · New Journal of Chemistry · 2021
We performed a structural study followed by theoretical analysis of the chemical descriptors and biological activity of a series of 5-thiophen-2-yl pyrazole derivatives as potent and selective cannabinoid-1 (CB1) receptor antagonists.