ADVIA 2120i peut-il remplacer le frottis sanguin ?
Mohammed Nazim Bennaoum, Hassiba Lazreg, Fatima Bechir, Fatima Zohra Bedjaoui, Mohamed Hammadi · Batna Journal of Medical Sciences (BJMS) · 2016
Introduction. The ADVIA 2120i is one of the most efficient analyzer used in hematology laboratories. In addition to the quantification of cells; it enables the detection of cytological abnormalities and alert biologist by specific alarms. Material and methods. We conducted a prospective study in the EHU Oran for 3 month. Overall, 146 blood samples were analyzed for which the analyser reported various cytological alarms and we reviewed them under the microscope as a gold standard. Results. This study allowed us to determine how the ADVIA 2120i can be helpful for routine use in screening cytological abnormalities. According to our results it turned out that the analyser is efficient for erythrocyte morphological abnormalities such as microcytosis, macrocytosis, hypochromy and anisocytosis. However, concerning leukocytes; we found a high rate of false positive cases, the specificity should be improved especially for detection of blasts.