Multiple Sequence Alignment
Wing-Kin Sung · 2009
Chapter 2 defined the alignment of two sequences and proposed methods for computing such alignment. This chapter extends the alignment concept to multiple sequences (that is, three or more sequences). Given a set of three or more DNA/RNA/protein sequences, multiple sequence alignment (MSA) aims to align those sequences by introducing gaps in each sequence. Figure 6.1 shows an example of a multiple sequence alignment of a set of HIV sequences.