"Iron-Based Nanoparticles, an Accurate and Powerful Sniper Targeting SARS- Cov-2"
Nura Adam Mohamed · Advancements in Cardiovascular Research · 2020
For the past few months, the world has been facing another coronavirus disease, COVID-19, caused by the SARS-CoV-2, giving the rise of a pandemic.In the vast majority of infected individuals, SARS-CoV-2 causes a mild ailment, but in some subjects, it progresses to severe disease or even death, with some groups being at high risk.However, SARS-CoV-2 is not the first coronavirus that caused serious, sometimes fatal, disease.Almost 20 years ago, SARS-CoV and later MERS were coronaviruses that led to severe diseases but did not result in pandemics.Some of the therapeutic lessons learned during the SARS-COV and MERS epidemics are being used now to treat COVID-19 patients, such as the still debated use of Chloroquine.However, there were other important preclinical studies performed around the time of SARS-COV and MERS epidemics that may also be useful applications in the COVID-19 context.This review highlights the benefits that could be gained by revising the non-conventional therapeutic approaches used in the previous coronavirus epidemics in improving the detection, treatment, and prevention tools and developing patient treatment follow-up strategies.Specifically, this review discusses the utilization of iron oxide nanoparticles due to their attractive properties.It also highlights the therapeutic opportunities and future directions of the iron oxide nanoparticles to be eventually employed in the current coronavirus pandemic.