Constrained Multi-scale Dense Connections for Accurate Biomedical Image Segmentation
Jiawei Zhang, Yanchun Zhang, Shanfeng Zhu, Xiaowei Xu · 2020
Biomedical image segmentation plays a critical role in clinical diagnosis and medical intervention. Recently, a variety of deep neural networks have boosted the biomedical image segmentation performance with a large margin, which adopts dense connections to explore rich representations in multiple scales. In multi-scale dense connections, features from all or most scales are fused or iteratively aggregated. In this paper, we propose constrained multi-scale dense connections (CMDC) for accurate biomedical image segmentation, which only fuse features from the nearest scales containing the most relevant appearance or semantic information. Based on CMDC, we further construct constraint multi-scale dense networks (CMD-Net) by applying CMDC to existing segmentation networks. Experiments across various architectures (including FCN-8s, U-Net, and DeepLabV3) and datasets (including GlaS, CRAG, KID, and ECS) demonstrate that CMD-Net not only outperforms existing schemes on both accuracy and efficiency but also can be easily generalized to a variety of segmentation networks. In addition, CMD-Net achieves state-of-the-art performance on two instance segmentation datasets, GlaS and CRAG.