Online monitoring of high dimensional physiological time series: A case study

Ursula Gather, Roland Fried, Vivian Lanius, Michael Imhoff · RePEc: Research Papers in Economics · 2001

In modern statistical process control, intelligent alarm systems have to be constructed which extract the important information from multivariate time series and detect critical "out-of control " states of the underlying mechanism quickly and reliably. Regarding high-dimensional time series, statistical methods for dimension reduction can help to compress the data into a few relevant variables before characteristic patterns in the data are searched for. In this paper we apply graphical models as a preliminary step preceding a factor analysis of the vital signs of critically ill patients in intensive care. Then a procedure for the online-detection of change points in univariate time series is applied to the original series and to each of the factors and the results are compared to the judgment of an experienced physician.

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