Kill Curve Determination
Debabrata Das, Debayan Das · 2020
Microorganisms can be regarded as elementary biological particles able to undertake functional relationships with their surrounding environment. Although most microorganisms are beneficial and necessary for human beings, microbial activities may also have undesirable consequences. Therefore, it is essential to kill a wide variety of microorganisms to minimize their destructive effects. The ability to destroy microorganisms is very important. It makes possible the aseptic technology techniques used in microbiological research, preservation of food, and treatment and prevention of disease. A microbial population is killed when exposed to a lethal agent. Cell death is generally logarithmic or exponential, i.e., the population will be reduced by the same fraction at constant intervals. Physical and chemical agents affecting microbial activities to such an extent as to deprive microbial particles of the expected reproductive capability can be regarded as lethal agents.