Protein-ligand binding interactions of imidazolium salts with SARS CoV-2
Dhurairaj Satheesh, Annamalai Rajendran, Kasi Chithra · Heliyon · 2020
The disease called severe acute respiratory syndrome ( SARS ) is a lifestyle intimidating viral contamination affected by a positive, single stranded novel RNA virus ( COVID-2019 ) from the enveloped coronaviruse family. The COVID-2019 virus has affected many people, scattering promptly, and researchers are attempting to find out medicines for its effectual cure in all over the globe. Chloroquine ( ChQ ) and its derivatives, an older drug used for the cure of malaria, is exposed to encompass a perceptible feasibility and commendable well-being in opposition to SARS CoV-2 associated pneumonia clinical trials conducted in China. Later on, a few investigations have been directed to find and present SARS CoV-2 antiviral medications. The aim of this present work deals with the potential binding interactions of some imidazolium salts with Nsp9 (Nonstructural protein 9) RNA binding protein of SARS CoV-2.