Statistical analysis and visualization of mass spectrometry data using R
Joseph Hennessey, Linda Berg Luecke, Rebekah L. Gundry · Graduate Medical Education Research Journal · 2020
Mass spectrometry (MS) identifies the mass-to-charge ratio of ions. In proteomic research, MS can be used to identify proteins in a sample by digesting proteins into peptides, ionizing the peptides, then detecting the peptides and fragments of peptides via a mass spectrometer. However, most proteomic experiments identify large numbers of proteins and at times it can be difficult to efficiency communicate results of large datasets. Therefore, we sought to apply various visualization techniques in R to allow for fast and effective processing of large MS datasets.