Computational identification of disulfiram and neratinib as putative SARS-CoV-2 main protease inhibitors

Viktor S. Stroylov, Igor V. Svitanko · Mendeleev Communications · 2020

Identification of disulfiram and neratinib as putative covalent inhibitors of SARS-CoV-2 virus main protease M pro by a combination of ‘on-top docking’ procedure, expert evaluation of potential hits and molecular dynamics is reported herein. This finding shows the importance of further development of virtual screening add-ons.

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