Building an I2B2-Based Population Repository for Clinical Research

Lydia González Cid, David Pérez-Rey, Alonso Enrique, Hernández Gema, Pablo Serrano Balazote, Miguel Pedrera‐Jiménez, Gómez Agustín, De Schepper Kristof, Titus Crepain, Brecht Claerhout · Studies in health technology and informatics · 2020

The present work provides a real-world case of the connection process of a hospital, 12 de Octubre University Hospital in Spain, to the TriNetX research network, transforming a compilation of disparate sources into a single harmonized repository which is automatically refreshed every day. It describes the different integration phases: terminology core datasets, specialized sources and eventually automatic refreshment. It also explains the work performed on semantic normalization of the involved clinical terminologies; as well as the resulting benefits the InSite platform services have enabled in the form of research opportunities for the hospital.

Read the paper · More papers on PaperTik