Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Ahmed M. Sayed, Amira R. Khattab, Asmaa M. AboulMagd, Hossam M. Hassan, Mostafa Ezzat Rateb, Hala Zaid, Usama Ramadan Abdelmohsen · RSC Advances · 2020
acetylglucopetunidin (31), isoxanthohumol (32) and ellagic acid (33), which are widely available in many edible fruits, obey both Lipinski's and Veber's rules of drug-likeness and thus possess high degrees of predicted bioavailability. These natural products are suggested as potential drug candidates for the development of anti-SARS-CoV-2 therapeutics in the near future.