The risk factors of abnormal circadian rhythm of blood pressure for Stanford B aortic dissection
Yijia Xie, Jieting Zhu, Muzi Li · 2019
Objective To investigate the risk factors of abnormal circadian rhythm of blood pressure in patients with Stanford type B aortic dissection. Methods Case information of 204 patients with Stanford type B aortic dissection admitted to vascular surgery department of the Second Xiangya hospital of Central South University from January 2016 to December 2018 were retrospectively analyzed. According to patients′ blood pressure rhythm during hospitalization, patients were divided into normal blood pressure circadian rhythm group (127 cases) and abnormal blood pressure circadian rhythm group (77 cases). Demographic information, ambulatory blood pressure monitoring results, comorbilities and medication treatment of the two groups were compared by using multivariate logistics regression analysis. Results The difference of the ambulatory blood pressure monitoring results {average night systolic blood pressure [(112.90±10.00)mmHg vs (128.15±15.20)mmHg], average night diastolic blood pressure [(66.40±7.91)mmHg vs (76.10±7.97)mmHg]}, comorbilities hyperlipidemia, renal failure, obstructive sleep apnea hypopnea syndrome, smoking and the medication treatment (analgesics, hypnotics and intravenous antihypertensive medicine) were statistically significant (P<0.05); multivariate logistic regression analysis showed that obstructive sleep apnea hypopnea syndrome and renal failure were independent risk factors of abnormal blood pressure rhythm in Stanford type B aortic dissection patients. While analgesics, hypnotics and intravenous antihypertensive medicine were protective factors. Conclusions The risk factors of abnormal circadian rhythm of blood pressure in patients with Stanford type B aortic dissection are renal failure and obstructive sleep apnea hypopnea syndrome. Protective factors were the usage of analgesics, hypnotics and intravenous antihypertensive medicine. Key words: Aneurysm, dissecting; Aortic diseases; Blood pressure; Risk factors