Cover Picture: Information Loss in Network Pharmacology (Mol. Inf. 7/2019)
Ingo Vogt, Jordi Mestres · Molecular Informatics · 2019
The cover picture shows the increase in uncertainty and loss of coverage on the vertices and edges, respectively, of a monopartite protein network projected from a bipartite drug-target network. Each circle in the graph represents a given protein coloured by protein family. The dashed gray line traces increasing information loss for proteins. Enzyme kinases, in orange, and aminergic G protein-coupled receptors (GPCRs), in light blue, are the protein families suffering from the highest degree of information loss. More Details in the Article by Ingo Vogt and Jordi Mestres, please see DOI: 10.1002/minf.201900032