Why have transgenic rodent models failed to successfully mimic Alzheimer’s disease. How can we develop effective drugs without them?
Rafael Franco, Eva Martínez‐Pinilla, Gemma Navarro · Expert Opinion on Drug Discovery · 2019
Alzheimer’s disease (AD) does not yet have an adequate animal model and, in addition, the mechanisms explored so far have not led to efficacious therapies. Some issues concerning animal models of A...