ROI-based Fully Automated Liver Registration in Multi-phase CT Images
Kentaro Saito, Huimin Lu, Hyoung Seop Kim, Shoji Kido, Masahiro Tanabe · International Conference on Control, Automation and Systems · 2018
In this paper, we propose a registration method for fully automated liver tumor detection. Multiple phases CT is used for the detection of the liver tumor because multiple phase CT can give different characteristic features of lesions for each time phases. Registration accuracy is important when obtaining image features from multiple time phases. However, since each time phases have different image density characteristics, therefore registration of multi-phase CT is a challenging task. In this paper, we propose a robust initial alignment method independent of changing image density features in each time phase, and deformable registration method with region of interests (ROI) as liver region extracted by U-Net. Our proposed method is evaluated on 15 patient image sets. This method is applied to the early arterial phase and the equilibrium phase to registries. Experimental results show that segmentation of early arterial phase is 83% and registration is 93% accuracy.