Corrigendum: Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity
Paolo Saul Coghi, Ivan Andreevich Yaremenko, Parichat Prommana, Peter S. Radulov, Mikhail A. Syroeshkin, Yu Jun Wu, Jia Ying Gao, Floria M. Gordillo, Simon Wing Fai Mok, Vincent Kam Wai Wong, Chairat Uthaipibull, Alexander Olegovich Terent'ev · ChemMedChem · 2018
On page 904, at the bottom of Table 2, the A549 IC50 value and selectivity index (SI) for paclitaxel are switched. The correct entries are: IC50=0.003 μm and SI=33.2. On page 904, under the section ′In vitro activity against cancer and normal cell lines′, the sentences: “All cyclic peroxides showed better selectivity index (SI) values for lung A549 cancer cell lines than artemisinin, chloroquine, and paclitaxel (Table 2, Figures S3 and S4). The selectivity index of tetraoxane 4 was 540 times higher than that of the reference compound paclitaxel,” should instead be: “All cyclic peroxides showed better selectivity index (SI) values for lung A549 cancer cell lines than artemisinin and chloroquine (Table 2, Figures S3 and S4). The selectivity index of tetraoxane 4 was 54 times higher than that of the reference compound chloroquine.” On page 906, under the section ′Electroanalytical study of peroxides′, the sentence: “Upon comparing the cytotoxicity on lung cancer cell lines, tetraoxane 3 has a higher oxidative capacity (Ep=−0.797 V, Table 3 and Figure S6) and higher selectivity index than paclitaxel,” should instead be: “Upon comparing the cytotoxicity on lung cancer cell lines, tetraoxane 3 has a higher oxidative capacity (Ep=−0.797 V, Table 3 and Figure S6) and higher selectivity index than chloroquine.”