Block relevance (BR) analysis and polarity descriptors in property-based drug design
Giuseppe Ermondi, Giulia Caron · ADMET & DMPK · 2018
Block Relevance (BR) analysis is a tool to interpret QSPR/PLS models which can provide the information content of any physicochemical determinant used in property-based drug discovery; its application for the characterization of experimental polarity descriptors is discussed.