Tumor localization using prone to supine surface based registration for breast cancer surgical planning
Felicia Alfano, F. Perez Garcia, Juan Enrique Ortuño, Mercedes Herrero Conde, Oscar Bueno Zamora, Felipe Ángel Calvo, Santiago Lizarraga, Andrés Santos, Javier Pascau, María J. Ledesma‐Carbayo · 2018
Breast cancer is the most common invasive cancer in women worldwide. Many women have their tumors detected before the lesions become clinically palpable. Occult lesions must be marked for the surgeon to ensure that they can be effectively resected. Image-guided wire localization (WGL) is the current standard of care for the excision of non-palpable carcinomas during breast conserving surgery (BCS). The integration of the information from multimodal imaging may be especially relevant in surgical planning as a complement or an alternative to WGL. The combination of information from images in different positions is especially difficult due to large breast deformation. This work presents a system to localize the target lesion in the operative supine position, starting from a prone Magnetic Resonance Imaging (MRI) study and performing a surface based registration. The evaluation of the methodology has been carried out in 13 cases achieving an average localization error of 6.7 mm.