Catalyst free Synthesis of Phenyl Hydrazones and their Biological Evaluation
Vikas B. Suryawanshi, Kalimoddin Inayatsab Momin, Abhay S. Bondge, Jairaj K. Dawale · Asian Journal of Research in Chemistry · 2018
An efficient route for the synthesis of aromatic hydrazones has been developed using simple protocol in water. The synthesis was completed by using commercially available starting material. Synthesized intermediates showed potent inhibition of Mycobacterium tuberculosis. The protocol shows broad substrate scope. The phenyl hydrazine shown drug like properties and is a good starting point for further exploration in antituberculosis drug discovery.