Rear Mirror View of some Biological Tools and Processes
Munishwar Nath Gupta, Ipsita Roy · Revista de Fomento Social · 2018
It is indeed remarkable how many developments in biological sciences have their origin in earlier ideas which were nearly forgotten and were buried.This review illustrates this with a few examples.Free solution capillary electrophoresis is a refined version of moving boundary electrophoresis.Immobilised metal affinity chromatography rests on the early work on protein precipitation with metal ions.The concept of proteins as templates was rejected in early times but has resurfaced in the context of prions and intrinsically disordered protein regions.The approach of using enzymes in organic solvents is credited to papers published in late 1980s; the idea though is as old at least as the beginning of the 20th century.