EFFECT OF AN AYURVEDIC COMBINATION IN ABNORMAL SERUM CHOLESTEROL LEVEL AND LIVER ENZYMES: A PILOT STUDY
Pratibha P Nair, M. K. Jithesh, Vivek P · International Journal of Research in Ayurveda and Pharmacy · 2018
The production of intrinsic cholesterol is mainly regulated by Liver.Nowadays abnormal liver function and resulting metabolic syndrome are very common mainly due to drastic changes in life styles.Hence a drug which is having liver protective effect along with effect in reducing cholesterol levels is more suitable for these conditions.10 patients having abnormal serum cholesterol levels and liver enzymes were selected for the study from the outpatient department of VPSV Ayurveda College Kottakkal and a pilot clinical trial was conducted using the Phanta kashaya (hot infusion) of 6 common drugs, namely Kiratathiktha [Andrographis paniculata (Burm.f.)Wall ex.Nees], Gokshura [Tribulus terrestris Linn.],Punarnava [Boerhavia diffusa Linn.],Bhringaraja [Eclipta alba (L.) Hassk.],Guduchi [Tinospora cordifolia Willd.Miers Ex Hook] and Bhoomyamalaki [Phyllanthes amarus Schum & Thonb] for 15 days.Serum cholesterol level and liver enzyme values were assessed before and after the study and paired t test was done for evaluation.Total cholesterol, very low-density lipoproteins and triglycerides level decreased significantly whereas level of high density lipoproteins significantly increased.In the case of transaminase values, even though there was reduction in the values, no statistical significance was observed.