Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: a novel series of potent antimicrobial and anticancer agents
Tarek H. Afifi, Rawda M. Okasha, Hany E. A. Ahmed, Janez Ilaš, Tarek M. Saleh, Alaa S. Abd‐El‐Aziz · PubMed · 2017
of 0.3 to 2 µg/mL. Apoptotic analysis was performed for the most potent compounds via caspase enzyme activity assays as a potential mechanism for their antiproliferative effects. Finally, the computational 2D QSAR and docking simulations were accomplished for structure-activity relationship analyses.