Measuring transmittance of human female breast cells through spectrophotometry and generating its equivalent circuit by prony modelling

Nida Nasir, Mahmoud Al Ahmad · 2017

This paper is an approach towards the electrical characterization of human female breast cancerous and non-cancerous cells. We measured the transmittance, over near-infrared (NIR) region of 640-1050 nm, of normal breast cells (MCF 10A) and cancer breast cells (MDA-MB-231) along with their growth medium DMEM/F12 (Dulbecco's Modified Eagle's Medium and Ham's Nutrient Mixture F12) through spectrophotometer. The measured transmittance signals have been used to synthesize equivalent electric circuit networks for cells and their medium, using MATLAB Prony toolbox. Prony toolbox has extracted the coefficients of transfer function that represents the signals, using which we generated the equivalent circuit of the transmittance by foster realization. The equivalent circuit comprises of the series combination of inductor, capacitor and resonators.

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