Approaches to target tractability assessment – a practical perspective
Kristin K. Brown, Michael M. Hann, Ami S. Lakdawala, Rita Santos, Pamela J. Thomas, Kieran P. Todd · MedChemComm · 2018
The assessment of the suitability of novel targets to intervention by different modalities, e.g. small molecules or antibodies, is increasingly seen as important in helping to select the most progressable targets at the outset of a drug discovery project.