Compensating anisotropy in histological serial sections with optical flow-based interpolation
Oleg Lobachev, Birte S. Steiniger, Michael Guthe · 2017
Histological serial sections allow for 3D representation of anatomical structures in microscopic to mesoscopic range. However, due to the nature of the acquisition, they suffer from severe anisotropy: 14-to-1 in a single average microscopic paraffin section. We present an interpolation method based on optical flow and show that standard interpolation methods are less suited for serial sections.