Structure–Based Drug Design of Quercetin and its Derivatives Against HMGB1
Kristina Simanjuntak, Jusman E. Simanjuntak, Rosmalena Rosmalena, Vivitri Dewi Prasasty · Biomedical & Pharmacology Journal · 2017
Introduction High mobility group box 1 (HMGB1) is a non-histone chromosomal and highly conserved protein that serves various roles in intracellular and extracellular systems. This group of proteins was appointed as the “high mobility group,” due to their rapid mobility properties in polyacryl