Exploring the Negative Likelihood Ratio and How It Can Be Used to Minimize False-Positives in Breast Imaging

Wei Tse Yang, Jay R. Parikh, A. Thomas Stavros, Pam Otto, Greg Maislin · American Journal of Roentgenology · 2017

OBJECTIVE: This article describes the definition and proposed utilization of negative likelihood ratios (NLRs) as statistical parameters in breast imaging. Examples with calculations are provided using BI-RADS category 4 subcategories. CONCLUSION: By auditing individual performance early and often against American College of Radiology benchmark positive predictive value ranges for the BI-RADS category 4 subcategories, and by fully understanding NLRs and their application in breast imaging, radiologists can minimize false-positive findings and unnecessary biopsies.

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