Adaptation of Synthesis Plans in Organic Chemistry
Jean Lieber, Amedeo Napoli · 1996
. This paper presents RESYN/CBR, a case-based planner dedicated to organic chemistry synthesis, from the viewpoint of its adaptation process. 1 INTRODUCTION Case-based reasoning [10] is a problem-solving paradigm based on the use of a case base where a case is a pair (problem, solution) and, in particular, a source case is a case from the case base. Given a problem to solve --the target problem-- a case-based reasoning system first searches a source case similar to the target problem (retrieval task) and then adapt this retrieved case in order to solve the target problem (adaptation task). This paper describes RESYN/CBR, an application of case-based planning to organic synthesis, from the viewpoint of case adaptation. Section 2 presents an overview of RESYN/CBR and its application domain. Section 3 describes the retrieval process. The adaptation process is described in section 4. It consists in matching the retrieved case to the target problem and reusing this retrieved case in order...