Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method
Francesco A. Aprile, Pietro Sormanni, Michele Perni, Paolo Arosio, Sara Snogerup Linse, Tuomas P. J. Knowles, Christopher Martin Dobson, Michele Vendruscolo · Science Advances · 2017
model overexpressing Aβ42. These results illustrate how the antibody scanning method described here can be used to readily obtain very small antibody libraries with extensive coverage of the sequences of target proteins.