QSAR study on Indole derivatives
Teodora E. Harsaa, Alex, ra M. Harsaa, L. Jantschib, Mircea Vasile Diudea · Journal of chemical and pharmaceutical research · 2015
This paper reviews the use of similarity searching in chemical databases, was performed on a set of 40 indole derivatives. The QSAR models describing log P and LD50 of this set of indole derivatives were validated by leaveone- out procedure, in the external test set and in a new version of prediction by using clusters of similarity.