SYNTHESIS OF PRECURSORS OF ANTIOSTEOPOROTIC AGENTS AND ITS QSAR STUDIES ON EGFR RECEPTOR INHIBITORS
Arvind Kumar Shrivastava, Alok Mukerjee, Paras Gupta, Neha Srivastava · 2014
The National Institutes of Health defines osteoporosis as a skeletal disorder characterized by compromised bone strength predisposing to an increased risk of fracture. However, currently there is no definition that is agreeable to both medical and scientific communities and its etiology is poorly understood. It is within this framework that the pharmaceutical industry is trying to develop new treatments for the so-called silent epidemic. This research article describes the osteoporosis as a disease and look forward for the update in its management with an aim to synthesize precursors of antiosteoporotic agents and QSAR studies on EGFR receptor inhibitors.