On the Terminations of Nerves in the Epidermis

Louis Antoine Ranvier · Journal of Cell Science · 1880

ABSTRACT It is well known that by the employment of chloride of gold it is possible to show the ultimate nerve-endings in tissues. But this reaction is not always followed with success if the original process of Cohnheim is pursued ; and in attempting, during the last few years, to render it more regular by combining the action of the gold with formic acid, Pritchard and Loewit have effected a very notable progress. At the same time the process of Loewit, although it gives far more constant results than any previous process, is not without its disadvantages. The solution of a third part of formic acid, in which the tissue is placed before being submitted to the action of the gold, alters the ultimate ramifications of the nerves, so that, on being fixed by the action of the gold, they are more or less altered.

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