Pass biological activity spectrum predictions of chromones in the enhanced open nci database browser
V. W. Banewar · Scholar Science Journals - International Journal of Biomedical Research · 2017
Chromone nucleus containing drugs have its own importance in drug chemistry.Chromones and its substituted compounds possess various pharmacological activities and acts as HIV -1 Protease inhibitors.The concept of Biological Activity Spectrum served as a basis for developing PASS (Prediction of Activity Spectra for Substances) software products.Evaluation of the general biological potential of molecule is possible using computer based program PASS that predicts more than 780 pharmacological effects on the basis of structural formula of compounds.The result of PASS studies shows that substituted and unsubstituted Chromone show many important biological activities.PASS also predicts some unwanted activities of Chromone, providing medicinal chemists with the means to increase the efficiency of projects.