67 Individual QT/RR relationship: average stability over time does not rule out an individual residual variability implication for the assessment of drug effect on the QT interval
Fabrice Extramiana, Pierre Maison‐Blanche, E. Badilini, Philippe Beaufils, Antoine Leenhardt · EP Europace · 2005
There were no differences in gender, age, treatment, time from the onset of symptoms of AMI to PTCA and extent of lesions in coronary arteries in both groups.Electrocardiographic data were obtained from 3-channel 24h Holter monitoring performed in the 5th day after AMI during awaking period (5-7 a.m).All repolarization parameters were corrected according to the Bazzet's formula: QT interval duration (QTc), dispersion of QT (QTdc), QTapex (QTapexc)and TapexTend (TapexTendc).QTd without correction was also used to evaluated the number of pts with QTd>30 ms.Results: the comparison of parameters revealed the differences between P-and P+ groups: for QTd (364-11 vs 264-7 ms, p30 ms differentiated P-and P+ pts, there were 13 pts in P-and 3 pts in P+ group (p<0.005).Conclusions: patients with the presence of microvascular integrity of the left ventricle were characterized by significantly lower values of all repolarization parameters.Lower QTd, QTdc and TapexTendc might indicate higher spatial and transmural homogeneity of this process after successful primary PTCA.Prospective follow-up will indicate the prognostic value of these findings.