Nonrigid 2D registration of fluoroscopic coronary artery image sequence with propagated deformation field

Taewoo Park, Seung Yeon Shin, Youngtaek Hong, Soochahn Lee, Hyuk‐Jae Chang, Il Dong Yun · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 2017

We propose a novel method for nonrigid registration of coronary arteries within frames of a fluoroscopic X-ray angiogram sequence with propagated deformation field. The aim is to remove the motion of coronary arteries in order to simplify further registration of the 3D vessel structure obtained from computed tomography angiography, with the x-ray sequence. The Proposed methodology comprises two stages: propagated adjacent pairwise nonrigid registration, and, sequence-wise fixed frame nonrigid registration. In the first stage, a propagated nonrigid transformation reduces the disparity search range for each frame sequentially. In the second stage, nonrigid registration is applied for all frames with a fixed target frame, thus generating a motion-aligned sequence. Experimental evaluation conducted on a set of 7 fluoroscopic angiograms resulted in reduced target registration error, compared to previous methods, showing the effectiveness of the proposed methodology.

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