Detectability of artificial lesions in anthropomorphic virtual breast phantoms of variable glandular fraction
Thomas J. Sauer, Christian G. Graff, Rongping Zeng, Maira Santana, Gregory M. Sturgeon, Hilde Bosmans, Stephen J. Glick, Xinyuan C. Chen, W. Paul Segars, Joseph Yuan-Chieh Lo · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · 2017
This work seeks to utilize a cohort of computational, patient-based breast phantoms and anthropomorphic lesions inserted therein to determine trends in breast lesion detectability as a function of several clinically relevant variables. One of the measures of local density proposed gives rise to a statistically significant trend in lesion detectability, and it is apparent that lesion type is also a predictor of relative detectability.