An Overview of Currently Available Antimalarials
Nikolay Yu. Gorobets, Yuriy V. Sedash, Brajendra K. Singh, Poonam Poonam, Brijesh Kumar Rathi · Current Topics in Medicinal Chemistry · 2017
BACKGROUND: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health. OBJECTIVE: Overview of currently available antimalarials. METHOD: Literary survey. RESULTS: The summarized data about different types of antimalarial therapies and their efficiency and modes of action. CONCLUSION: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action.