Efficient space and time multicomparison of genomes

Xavier Messeguer, Mario M. Carrillo Huerta · 2003

The comparison of genomes is based on substrings, called MUMs, that appear only once in each genome and are maximal. The set of MUMs determines the skeleton from which a global comparison can be established. The search of MUMs is handled with Suffix trees which are those trees that store all suffixes of a given sequence. The searching algorithm builds a generalized suffixtree for each pair and finds the MUMs between them.

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