[Value of Analyzing Hemoglobin A2 by ROC Curve for Screening Thalassemia].
Tianwen He, Lihua Yu, Hao Guo, Yixia Wang, Li Lin Du, Tenglong Yuan, Yan-Xia Zhang, Mingyong Luo, Aihua Yin · PubMed · 2016
OBJECTIVE: ) for screening thalassemia. METHODS: ) level was analyzed by the full automatic capillary electrophoresis technique, and the genotypes of thalassemia were detected. RESULTS: for screening silent α-thalassemia, α-thalassemia trait, intermedia α-thalassemia and β-thalassemia trait were 2.85%, 2.65%, 2.25% and 3.45%, respectively; the areas under receiver operator characteristic (ROC) curve were 0.709, 0.839, 0.979 and 0.997 respectively; the sensitivities were 0.481, 0.721, 0.953 and 0.994, and the specificities were 0.846, 0.837, 0.929 and 0.969 respectively. CONCLUSION: level.