3. Structure- and ligand-based approaches in drug designing
Sumitra Nain, Garima Mathur, Girish Kumar Gupta, Sarvesh Paliwal · 2016
This chapter enlightens the new concept of structure and ligand based drug designing. It is time saving technique and most reliable as in this method target is being modulated to obtain desired activity despite of hit and trial method which is tedious and less reliable. This chapter also comprises of different steps to be taken during the process of structure and ligand based drug designing. 2D QSAR and 3D QSAR are being discussed by including approaches, descriptors as well as different parameters used in QSAR studies.