1. Overview of chemical drug design
Sreekanth Thota · 2016
Now a days identifying the novel medicines, drug design is the inventive process. Drug design that relies on the knowledge of the structure-based drug design is nothing but three-dimensional structure of the biomolecular target. The drug design approach has already proven as quite useful method in identification of many successful drugs. Computational approaches have become important tools to accelerate the development of epigenic inhibitors helping in the selection, design and lead identification of new compounds. The drug discovery research of the compound gives significant results if computational technology methods compliment in vitro experiments. These compounds may give more favorable ADME and toxicological profiles. This chapter provides an overview of some techniques used in chemical drug design to date.