The study of blood flow using indicator dilution techniques

David A. Lane · Spiral (Imperial College London) · 1974

An in v e s tig a tio n has been made o f the d isp e rsio n o f the ra d ioa c tiv e ly la b e lle d c o n s titu e n ts o f blood du rin g flo w .In lam inar flo w down a long s tr a ig h t tube the n o n -c e llu la r components are dispersed by lam inar convection and in d ic a to r d iffu s io n .I t has been found th a t Chapter 3 (c o n t' d) page T a ll p a tte rn taps Pressure re g u la tio n and determ ination SO D ire c t flo w ra tc ,Q , and volume, Va, determ in atio n V iscom etric determ inations SI Model vascu la r bed system SI D e te ctio n , counting and reco rding apparatus C a lib ra tio n o f m o n ito rin g apparatus Sampling systems Temperature c o n tro l Experimental procedure C a lc u la tio n o f flo w ra te (F ), mean t r a n s it times ( t .t n) and vessel volumes (V, Va ) using the in d ic a to r d ilu tio n theory S o lu tio n s , suspensions and in d ic a to rs Iodide ( I ) in KGl s o lu tio n Blood, plasma and red c e ll suspensions Plasma in d ic a to rs Red c e ll la b e llin g Red c e ll f l e x i b i l i t y measurements Chapter 4 .RESULTS -STRAIGHT TUBE SYSTEM 1 3 lI in 2H KCl s o lu tio n © £ Rb in plasma and whole blood 1 3 131 HSA *• I in blood and plasma

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