Model-based methods in analysis of biomedical images
Tim F. Cootes · 1999
Abstract Biomedical images usually contain complex objects, which will vary in appearance significantly from one image to another. Attempting to measure or detect the presence of particular structures in such images can be a daunting task. The inherent variability will thwart naive schemes. However, by using models which can cope with the variability it is possible to successfully analyse complex images. Here we will consider a number of methods where the model represents the expected shape and local greylevel structure of a target object in an image. Model-based methods make use of a prior model of what is expected in the image, and typically attempt to find the best match of the model to the data in a new image. Having matched the model, one can then make measurements or test whether the target is actually present.