Detection of breast cancer using non-invasive X-ray diffraction technique of hair: A preliminary study

Asghar Maziar, Daryoush Shahbazi‐Gahrouei, Mahdi Tavakoli, Vahid Changizi, Z. Ghasemian · Internatuinal Journal of Radiation Research · 2016

Background: An early diagnosis of breast cancer relates directly to an accurate treatment plan and strategy.Early detec on of breast cancer before its development would be a significant reduc on of morbidity and mortality rates.The aim of this preliminary study is to inves gate the sensi vity of Wide Angle X-ray diffrac on (WAXRD) method on women hair samples of healthy and breast cancer pa ents in comparison with other modali es such as synchrotron based XRD beam and mammography.Materials and Methods: Hair samples were taken from occipital region of skull from healthy and breast cancer pa ents (43 women) were analyzed using X-ray diffrac on and the results were analyzed and compared with mammography and pathology reports.Results: The results of analyzed samples showed the sensi vity for purposed WAXRD method was 86% in comparison with synchrotron based XRD beam (64%) and also with mammography (70%).Conclusion: This non-invasive method is less harmful and is more sensi ve than the two other methods and help the physicians for choosing accurate treatment plan.

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