Genetic Algorithm for Biomarker Search Problem and Class Prediction

Shabia Shabir Khan, S. M. K. Quadri, Marco Peer · International Journal of Intelligent Systems and Applications · 2016

In the field of optimizat ion, Genetic Algorith m that incorporates the process of evolution plays an important role in finding the best solution to a problem.One of the main tasks that arise in the medical field is to search a finite nu mber of factors or features that actually affect or predict the survival of the patients especially with poor prognosis disease, thus helping them in early diagnosis.This paper discusses the various steps that are performed in genetic algorith m and how it is going to help in ext racting knowledge out of h igh dimensional med ical dataset.The more the attributes or features, the more difficult it is to correctly predict the class of that sample o r instance.This is because of inefficient, useless, noisy attributes in the dataset.So, here the main aim is to search the features or genes that can strongly predict the class of subject (patient) i.e. healthy or cancerous and thus help in early detection and treatment.

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