THE HUMAN NEUROSCANNING PROJECT
Jan Modersitzki · 2003
Abstract This chapter presents a typical application for image registration. The particular goal of the Human Neuro-Scanning Project is a three-dimensional reconstruction down to particular neurons of a whole human brain based on microscopic modalities. The workflow that leads to stained histological slides and their digitalization is explained. The process is illustrated by various figures showing the sectioning process, the paraffin embedded brain, a sectioned slide, and the digitalization. It is shown that these processes lead to unwanted highly non-linear distortion of the sections that inhibits a direct reconstruction.