Retrospective Quantitative Structure—Activity Relationship (QSAR) Analysis of Tetrazolo- and Triazoloquinolines, a Series of Rice Blast Control Agents
Barry A. Dreikorn, Gregory L. Durst · ACS symposium series · 1995
Although the SAR of the tetrazolo- and triazoloquinolines that culminated in the discovery of tricyclazole was carried out more than twenty years ago, a QSAR analysis of the structures had never been conducted. This paper will compare and contrast the conclusions reached in the "classical" SAR study with those suggested by modern computer-assisted design techniques.